Bryan Scyphers received a bachelor's degree in education from Virginia Tech and a master's degree in higher education from the University of North Carolina. Scyphers also holds the Certified Emergency Manager credential.

He retired as a college associate dean in 2008, following 30 years of service in North Carolina. He is currently an emergency planning analyst for the U.S. Department of Health and Human Services' National Disaster Medical System, serving as a planning section chief on the HHS Incident Reponse Coordination Team. This team coordinates the federal ESF-8 Public Health and Medical response to disasters or national sepcial security events. Since 1976, he has been a nationally registered paramedic with emergency medical service experience and has responded to more than 8,000 EMS calls.

He was a student athletic trainer for Virginia Tech's football team and was a trainer with the San Francisco Giants baseball organization.

He and his wife, Marsha, live in Winston-Salem, N.C.